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Article

Genetics of variation in HOMA-IR and cardiovascular risk factors in Mexican-Americans.

Journal of molecular medicine (Berlin, Germany) - 1 Mar 2008

Voruganti V Saroja, Lopez-Alvarenga Juan C, Nath Subrata D, Rainwater David L, Bauer Richard, Cole Shelley A, Maccluer Jean W, Blangero John, Comuzzie Anthony G

Abstract excerpt

Insulin resistance is a major biochemical defect underlying the pathogenesis of cardiovascular disease (CVD). Mexican-Americans are known to have an unfavorable cardiovascular profile. Thus, the aim of this study was to investigate the genetic effect on variation in HOMA-IR and to evaluate its genetic correlations with other phenotypes related to risk of CVD in Mexican-Americans. The homeostatic model assessment...

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PMID: 18204828
DOI: 10.1007/s00109-007-0273-3

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PAH

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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