Article
Nonadaptive explanations for signatures of partial selective sweeps in Drosophila.
Molecular biology and evolution - 1 Jun 2008
Macpherson J Michael, González Josefa, Witten Daniela M, Davis Jerel C, Rosenberg Noah A, Hirsh Aaron E, Petrov Dmitri A
Abstract excerpt
A beneficial mutation that has nearly but not yet fixed in a population produces a characteristic haplotype configuration, called a partial selective sweep. Whether nonadaptive processes might generate similar haplotype configurations has not been extensively explored. Here, we consider 5 population genetic data sets taken from regions flanking high-frequency transposable elements in North American strains of...
Topics
- Adaptation, Biological
- Animals
- Base Sequence
- Computer Simulation
- DNA Transposable Elements
- Drosophila melanogaster
- Genomics
- Models, Genetic
- Molecular Sequence Data
- Mutation
- Recombination, Genetic