Article
Pathogenic diversity among Chlamydia trachomatis ocular strains in nonhuman primates is affected by subtle genomic variations.
The Journal of infectious diseases - 1 Feb 2008
Kari Laszlo, Whitmire William M, Carlson John H, Crane Deborah D, Reveneau Nathalie, Nelson David E, Mabey David C W, Bailey Robin L, Holland Martin J, McClarty Grant, Caldwell Harlan D
Abstract excerpt
Chlamydia trachomatis is the etiological agent of trachoma, the leading cause of preventable blindness. Trachoma presents distinct clinical syndromes ranging from mild and self-limiting to severe inflammatory disease. The underlying host and pathogen factors responsible for these diverse clinical outcomes are unclear. To assess the role played by pathogen variation in disease outcome, we analyzed the genomes of 4...
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