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Article

An HIV-1 clade C DNA prime, NYVAC boost vaccine regimen induces reliable, polyfunctional, and long-lasting T cell responses.

The Journal of experimental medicine - 21 Jan 2008

Harari Alexandre, Bart Pierre-Alexandre, Stöhr Wolfgang, Tapia Gonzalo, Garcia Miguel, Medjitna-Rais Emmanuelle, Burnet Séverine, Cellerai Cristina, Erlwein Otto, Barber Tristan, Moog Christiane, Liljestrom Peter, Wagner Ralf, Wolf Hans, Kraehenbuhl Jean-Pierre, Esteban Mariano, Heeney Jonathan, Frachette Marie-Joelle, Tartaglia James, McCormack Sheena, Babiker Abdel, Weber Jonathan, Pantaleo Giuseppe

Abstract excerpt

The EuroVacc 02 phase I trial has evaluated the safety and immunogenicity of a prime-boost regimen comprising recombinant DNA and the poxvirus vector NYVAC, both expressing a common immunogen consisting of Env, Gag, Pol, and Nef polypeptide domain from human immunodeficiency virus (HIV)-1 clade C...

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Source

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Identifiers

PMID: 18195071
DOI: 10.1084/jem.20071331
PMCID: PMC2234371

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18195071-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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