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Enhancing poxvirus vectors vaccine immunogenicity

5 May 2014

Abstract excerpt

Attenuated recombinant poxvirus vectors expressing heterologous antigens from pathogens are currently at various stages in clinical trials with the aim to establish their efficacy. This is because these vectors have shown excellent safety profiles, significant immunogenicity against foreign expressed antigens and are able to induce protective immune responses. In view of the limited efficacy triggered by some...

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PMID: 25424927
DOI: 10.4161/hv.28974

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