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Article

A novel ATP1A2 gene mutation in an Irish familial hemiplegic migraine kindred.

Headache - 1 Jan 2008

Fernandez Desiree M, Hand Collette K, Sweeney Brian J, Parfrey Nollaig A

Abstract excerpt

OBJECTIVE: We studied a large Irish Caucasian pedigree with familial hemiplegic migraine (FHM) with the aim of finding the causative gene mutation. BACKGROUND: FHM is a rare autosomal-dominant subtype of migraine with aura, which is linked to 4 loci on chromosomes 19p13, 1q23, 2q24, and 1q31. The mutations responsible for hemiplegic migraine have been described in the CACNA1A gene (chromosome 19p13), ATP1A2 gene...

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PMID: 18184292
DOI: 10.1111/j.1526-4610.2007.00848.x

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