Article
Minocycline-induced DRESS: evidence for accumulation of the culprit drug.
Dermatology (Basel, Switzerland) - 1 Jan 2008
Maubec Eve, Wolkenstein Pierre, Loriot Marie-Anne, Wechsler Janine, Mulot Claire, Beaune Philippe, Revuz Jean, Roujeau Jean-Claude
Abstract excerpt
BACKGROUND: Minocycline-induced drug rash with eosinophilia and systemic symptoms (DRESS) may have a prolonged course, especially in African and African-American patients. OBJECTIVES: To determine if a prolonged course of minocycline-induced DRESS was associated with an accumulation of the culprit drug. PATIENTS AND METHODS: We determined plasma and skin levels of minocycline in patients with minocycline-induced...
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