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Phenotypic differences in behavior, physiology and neurochemistry between rats selected for tameness and for defensive aggression towards humans.

Hormones and behavior - 1 Mar 2008

Albert Frank W, Shchepina Olesya, Winter Christine, Römpler Holger, Teupser Daniel, Palme Rupert, Ceglarek Uta, Kratzsch Jürgen, Sohr Reinhard, Trut Lyudmila N, Thiery Joachim, Morgenstern Rudolf, Plyusnina Irina Z, Schöneberg Torsten, Pääbo Svante

Abstract excerpt

To better understand the biology of tameness, i.e. tolerance of human presence and handling, we analyzed two lines of wild-derived rats (Rattus norvegicus) artificially selected for tameness and defensive aggression towards humans. In response to a gloved human hand, tame rats tolerated handling, whereas aggressive rats attacked. Cross-fostering showed that these behavioral differences are not caused by postnatal...

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Identifiers

PMID: 18177873
DOI: 10.1016/j.yhbeh.2007.11.010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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