Article
Lack of association between leptin G2548A gene polymorphism and Behçet's disease.
Journal of the European Academy of Dermatology and Venereology : JEADV - 1 Jan 2007
Aydin F, Kara N, Senturk N, Gunes S, Canturk M T, Bagci H, Bek Y, Turanli A Y
Abstract excerpt
BACKGROUND: Behçet's disease is a chronic, multisystem, inflammatory disease characterized by the predominance of T-helper 1 cytokines. The disease is also characterized by infiltration of lymphocytes and neutrophils into the affected tissues. Because cytokines are involved in the regulation of lymphocyte and phagocyte functions, they may play an important role in the pathogenesis of Behçet's disease. Leptin, a...
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