Electrophoretic techniques applied to the detection and analysis of the human microsatellite DG10s478.

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Article

Electrophoretic techniques applied to the detection and analysis of the human microsatellite DG10s478.

Journal of biomolecular techniques : JBT - 1 Dec 2007

Taylor Clara Y, Guillén Isabel A, Nazabal Marcelo, Fernández Julio R, Silva José A

Abstract excerpt

Short nucleotide repetitions (STRs) are commonly used as genetic markers; thus their detection and analysis constitutes a very important tool for the mapping of genetic diseases, as well as for gathering information about genetic polymorphisms at the population level. STRs can be detected with agarose- or acrylamide-based electrophoretic techniques, followed by visualization of the DNA sample with ethidium...

Topics

Alleles
Diabetes Mellitus, Type 2
Electrophoresis, Polyacrylamide Gel
Feasibility Studies
Genetic Markers
Genome, Human
Genotype
Humans
Microsatellite Repeats
Polymorphism, Genetic
Reverse Transcriptase Polymerase Chain Reaction
TCF Transcription Factors
Transcription Factor 7-Like 2 Protein

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Identifiers

PMID: 18166673
PMCID: PMC2392994

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