Article
Interaction with host SGS3 is required for suppression of RNA silencing by tomato yellow leaf curl virus V2 protein.
Proceedings of the National Academy of Sciences of the United States of America - 8 Jan 2008
Glick Efrat, Zrachya Avi, Levy Yael, Mett Anahit, Gidoni David, Belausov Eduard, Citovsky Vitaly, Gafni Yedidya
Abstract excerpt
The V2 protein of tomato yellow leaf curl geminivirus (TYLCV) functions as an RNA-silencing suppressor that counteracts the innate immune response of the host plant. The host-cell target of V2, however, remains unknown. Here we show that V2 interacts directly with SlSGS3, the tomato homolog of the Arabidopsis SGS3 protein (AtSGS3), which is known to be involved in the RNA-silencing pathway. SlSGS3 genetically...
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