Article
Do mood symptoms subdivide the schizophrenia phenotype? Association of the GMP6A gene with a depression subgroup.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Sept 2008
Boks Marco P M, Hoogendoorn Mechteld, Jungerius Bart J, Bakker Steven C, Sommer Iris E, Sinke Richard J, Ophoff Roel A, Kahn René S
Abstract excerpt
Genetic studies of clinically defined subgroups of schizophrenia patients may reduce the phenotypic heterogeneity of schizophrenia and thus facilitate the identification of genes that confer risk to this disorder. Several latent class analyses have provided subgroups of psychotic disorders that show considerable consistency over these studies. The presence or absence of mood symptoms was found to contribute most...
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