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Article

Femoral atherosclerosis in heterozygous familial hypercholesterolemia: influence of the genetic defect.

Arteriosclerosis, thrombosis, and vascular biology - 1 Mar 2008

Junyent Mireia, Gilabert Rosa, Zambón Daniel, Pocoví Miguel, Mallén Miguel, Cofán Montserrat, Núñez Isabel, Civeira Fernando, Tejedor Diego, Ros Emilio

Abstract excerpt

OBJECTIVE: The purpose of this study was to assess femoral atherosclerosis by ultrasound in patients with molecularly defined heterozygous familial hypercholesterolemia (FH) in comparison with matched control subjects and in relation to mutational class in the LDL receptor and apolipoprotein B (APOB) genes. METHODS AND RESULTS: Femoral intima-media thickness (IMT) and plaque were evaluated in 146 FH patients...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18096825
DOI: 10.1161/ATVBAHA.107.153841

Genes

APOB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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