Article
The Caenorhabditis elegans NR4A nuclear receptor is required for spermatheca morphogenesis.
Developmental biology - 15 Jan 2008
Gissendanner Chris R, Kelley Kristopher, Nguyen Tri Q, Hoener Marius C, Sluder Ann E, Maina Claude V
Abstract excerpt
The gene nhr-6 encodes the Caenorhabditis elegans ortholog of the NR4A nuclear receptor. We determined the biological functions of NHR-6 through the isolation and characterization of a deletion allele of nhr-6, lg6001. We demonstrate that nhr-6 has an essential role in the development of the C. elegans somatic gonad. Specifically, nhr-6 is required for the development of the hermaphrodite spermatheca, a somatic...
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