Article
Association between polymorphisms in MTHFR and APOA5 and metabolic syndrome in the Greek population.
Genetic testing and molecular biomarkers - 1 Sept 2011
Vasilopoulos Yiannis, Sarafidou Theologia, Bagiatis Vasilis, Skriapa Lambrini, Goutzelas Yiannis, Pervanidou Panagiota, Lazopoulou Natalia, Chrousos George P, Mamuris Zissis
Abstract excerpt
Impaired energy homeostasis and low-grade inflammation have been related to components of the metabolic syndrome (MetS) such as dyslipidemia, obesity, and insulin resistance. Single-nucleotide polymorphisms in the genes encoding for IL-6 (g.-634G>C; c.174G>C), TNFα (g.-308G>A), methylenetetrahydrofolate reductase (MTHFR) (c.677C>T), APOC3 (c.3175C>G), and APOA5 (g.-1131T>C) have been implicated in the processes...
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