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Article

TREX1 polymorphisms associated with autoantibodies in patients with systemic lupus erythematosus.

Rheumatology international - 1 Jun 2008

Hur Jin-Wuk, Sung Yoon-Kyoung, Shin Hyoung Doo, Park Byung Lae, Cheong Hyun Sub, Bae Sang-Cheol

Abstract excerpt

Three-prime repair exonucleases 1 and 2 (TREX1 and TREX2) play a role in the metabolism and clearance of DNA. The objective of this study was to confirm whether polymorphisms of TREX1 and TREX2 are associated with genetic susceptibility to systemic lupus erythematosus (SLE), and examine associations with autoantibodies (auto-Abs) in SLE. We investigated the genetic variants in 24 Korean individuals by direct...

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Share to Antibodies, Antinuclear
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18092167
DOI: 10.1007/s00296-007-0509-0

Genes

TREX1
TREX2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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