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Article

Triptolide, a component of Chinese herbal medicine, modulates the functional phenotype of dendritic cells.

Transplantation - 15 Dec 2007

Liu Yan, Chen Yan, Lamb Jonathan R, Tam Paul K H

Abstract excerpt

BACKGROUND: Triptolide (TPT) is a component of the Chinese herb Triptergium wilfordii and has potent immunosuppressive and anti-inflammatory effects. Since dendritic cells (DCs) play a critical role in the initiation of alloimmune responses to foreign grafts, the aim of the present study was to evaluate the effects of TPT in the functional phenotype of bone marrow (BM)-derived DCs. METHODS: BM-derived DCs were...

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Source

Identifiers

PMID: 18091529
DOI: 10.1097/01.tp.0000289990.55668.0d

Genes

TLR4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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