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Article

cis-Regulatory changes in Kit ligand expression and parallel evolution of pigmentation in sticklebacks and humans.

Cell - 14 Dec 2007

Miller Craig T, Beleza Sandra, Pollen Alex A, Schluter Dolph, Kittles Rick A, Shriver Mark D, Kingsley David M

Abstract excerpt

Dramatic pigmentation changes have evolved within most vertebrate groups, including fish and humans. Here we use genetic crosses in sticklebacks to investigate the parallel origin of pigmentation changes in natural populations. High-resolution mapping and expression experiments show that light gills and light ventrums map to a divergent regulatory allele of the Kit ligand (Kitlg) gene. The divergent allele...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Regulatory Sequences, Nucleic Acid

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Source

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Identifiers

PMID: 18083106
DOI: 10.1016/j.cell.2007.10.055
PMCID: PMC2900316

Genes

KITLG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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