Article
Biological and clinical relevance of matrix metalloproteinases 2 and 9 in acute myeloid leukaemias and myelodysplastic syndromes.
European journal of haematology - 1 Mar 2008
Travaglino Erica, Benatti Chiara, Malcovati Luca, Della Porta Matteo Giovanni, Gallì Anna, Bonetti Elisa, Rosti Vittorio, Cazzola Mario, Invernizzi Rosangela
Abstract excerpt
We analysed by immunocytochemistry metalloproteinase (MMP)-2 and MMP-9 expression in bone marrow cells from 54 acute myeloid leukaemia (AML) patients, 153 myelodysplastic syndrome (MDS) patients, and 52 non-haemopathic subjects, in order to evaluate whether MMP expression abnormalities were associated with relevant laboratory or clinical findings. In normal samples MMP-2 was detected in rare myeloid cells, MMP-9...
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