Article
Expression of a novel 90-kDa protein, Lsd90, involved in the metabolism of very long-chain fatty acid-containing phospholipids in a mitosis-defective fission yeast mutant.
Journal of biochemistry - 1 Mar 2008
Yokoyama Kazuaki, Nakagawa Miyuki, Satoh Masayuki, Saitoh Shigeaki, Dohmae Naoshi, Harada Ayako, Satoh Noriko, Karasawa Ken, Takio Koji, Yanagida Mitsuhiro, Inoue Keizo
Abstract excerpt
The fission yeast lsd1/fas2 strain carries a temperature-sensitive mutation of the fatty-acid-synthase alpha-subunit, exhibiting an aberrant mitosis lsd phenotype, with accumulation of very-long-chain fatty-acid-containing phospholipid (VLCFA-PL). A novel 90-kDa protein, Lsd90 (SPBC16E9.16c), was found to be newly expressed in small particle-like structures in lsd1/fas2 cells under restrictive conditions. Two...
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