Expression of a novel 90-kDa protein, Lsd90, involved in the metabolism of very long-chain fatty acid-containing phospholipids in a mitosis-defective fission yeast mutant.

doi:10.1093/jb/mvm232

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Article

Expression of a novel 90-kDa protein, Lsd90, involved in the metabolism of very long-chain fatty acid-containing phospholipids in a mitosis-defective fission yeast mutant.

Journal of biochemistry - 1 Mar 2008

Yokoyama Kazuaki, Nakagawa Miyuki, Satoh Masayuki, Saitoh Shigeaki, Dohmae Naoshi, Harada Ayako, Satoh Noriko, Karasawa Ken, Takio Koji, Yanagida Mitsuhiro, Inoue Keizo

Abstract excerpt

The fission yeast lsd1/fas2 strain carries a temperature-sensitive mutation of the fatty-acid-synthase alpha-subunit, exhibiting an aberrant mitosis lsd phenotype, with accumulation of very-long-chain fatty-acid-containing phospholipid (VLCFA-PL). A novel 90-kDa protein, Lsd90 (SPBC16E9.16c), was found to be newly expressed in small particle-like structures in lsd1/fas2 cells under restrictive conditions. Two...

Topics

Amino Acid Sequence
Base Sequence
Fatty Acids
Gene Expression Regulation, Fungal
Mitosis
Molecular Sequence Data
Molecular Weight
Mutation
Phenotype
Phospholipids

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Protein Transport

Proteome

RNA, Messenger

Schizosaccharomyces

Schizosaccharomyces pombe Proteins

Sequence Analysis, Protein

Subcellular Fractions

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PMID: 18079165
DOI: 10.1093/jb/mvm232

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