Article
Beta-catenin mutations do not contribute to cardiac fibroma pathogenesis.
Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society - 1 Jan 2000
Miller Dylan V, Wang Huamin, Wang Hua, Fealey Michael E, Tazelaar Henry D
Abstract excerpt
Cardiac fibromas are the 2nd most common benign cardiac tumor occurring in children and bear a striking morphologic resemblance to soft tissue or desmoid fibromatosis. Since activating mutations in beta-catenin are common in desmoid fibromatosis as well as other spindle cell proliferations, the a...
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