Article
Protein tyrosine kinase 2beta as a candidate gene for hypertension.
Pharmacogenetics and genomics - 1 Nov 2007
Kamide Kei, Kokubo Yoshihiro, Fukuhara Shigetomo, Hanada Hironori, Yang Jin, Kada Akiko, Nagura Junko, Takiuchi Shin, Horio Takeshi, Kawano Yuhei, Okayama Akira, Tomoike Hitonobu, Miyata Toshiyuki
Abstract excerpt
Protein tyrosine kinase 2beta (PTK2B) is a member of the focal adhesion kinase family and is activated by angiotensin II through Ca2+-dependent pathways. An evidence exists that PTK2B is involved in cell growth, vascular contraction, inflammatory responses, and salt and water retention through ac...
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