Article
Characterization of toxic effects of sediment-associated organic pollutants using the lambda transgenic medaka.
Environmental science & technology - 15 Nov 2007
Cachot Jerome, Law Mac, Pottier Didier, Peluhet Laurent, Norris Michelle, Budzinski Helene, Winn Richard
Abstract excerpt
A novel sediment-contact assay using embryos of the transgenic medaka was developed to fully characterize the toxic effects induced by exposure to a mixture of organic pollutants in sediments. Embryos of the lambda transgenic medaka were exposed for 10 days to a clean reference sediment spiked with either the solvent alone, benzo[a]pyrene (B[a]P), or three concentrations (0.3x, 1x, and 2x) of an organic extract...
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