Article
The effect of Trp83 mutant on the properties of CopC.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy - 1 Jul 2008
Li Hui-Qin, Zheng Xiao-Yan, Pang Er-Guo, Zhao Ya-Qin, Yang Bin-Sheng
Abstract excerpt
CopC, a protein involved in copper resistance, is essentially constituted by two sheets forming a Greek key beta barrel motif. The aromatic ring of Trp83, sandwiched between the two beta sheets, has numerous contacts with residues in strands beta and stabilizes the protein fold. In the paper Trp83 was mutated to Leu to study the effect of this mutation on CopC by means of fluorescence spectra and UV spectra. The...
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