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Identification and functional analysis of novel (p)ppGpp synthetase genes in Bacillus subtilis.

Molecular microbiology - 1 Jan 2008

Nanamiya Hideaki, Kasai Koji, Nozawa Akira, Yun Choong-Soo, Narisawa Takakuni, Murakami Kana, Natori Yousuke, Kawamura Fujio, Tozawa Yuzuru

Abstract excerpt

Bacterial alarmone (p)ppGpp, is a global regulator responsible for the stringent control. Two homologous (p)ppGpp synthetases, RelA and SpoT, have been identified and characterized in Escherichia coli, whereas Gram-positive bacteria such as Bacillus subtilis have been thought to possess only a single RelA-SpoT enzyme. We have now identified two genes, yjbM and ywaC, in B. subtilis that encode a novel type of...

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PMID: 18067544
DOI: 10.1111/j.1365-2958.2007.06018.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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