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Article

Differential gene expression in ACTH -secreting and non-functioning pituitary tumors

1 Dec 2007

Abstract excerpt

OBJECTIVE: Differential expression of several genes between ACTH-secreting pituitary tumors causing Cushing' disease (CD), silent corticotroph adenoma (SCA), and non-functioning pituitary tumors (NFT) was investigated. DESIGN AND METHODS: We used tissue specimens from 35 pituitary tumors (12 CD, 8 SCA, and 15 NFT). Steady-state mRNA levels of the genes related to proopiomelanocortin (POMC) transcription,...

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PMID: 18057378
DOI: 10.1530/eje-07-0428

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