Article
Association studies for untyped markers with TUNA.
Bioinformatics (Oxford, England) - 1 Feb 2008
Wen Xiaoquan, Nicolae Dan L
Abstract excerpt
UNLABELLED: The software package TUNA (Testing UNtyped Alleles) implements a fast and efficient algorithm for testing association of genotyped and ungenotyped variants in genome-wide case-control studies. TUNA uses Linkage Disequilibrium (LD) information from existing comprehensive variation datasets such as HapMap to construct databases of frequency predictors using linear combination of haplotype frequencies of...
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