Article
Functional genomic characterization of mRNAs associated with TcPUF6, a pumilio-like protein from Trypanosoma cruzi.
The Journal of biological chemistry - 28 Mar 2008
Dallagiovanna Bruno, Correa Alejandro, Probst Christian M, Holetz Fabiola, Smircich Pablo, de Aguiar Alessandra Melo, Mansur Fernanda, da Silva Claudio Vieira, Mortara Renato A, Garat Beatriz, Buck Gregory A, Goldenberg Samuel, Krieger Marco A
Abstract excerpt
Trypanosoma cruzi is the protozoan parasite that causes Chagas disease or American trypanosomiasis. Kinetoplastid parasites could be considered as model organisms for studying factors involved in posttranscriptional regulation because they control gene expression almost exclusively at this level. The PUF (Pumilio/FBF1) protein family regulates mRNA stability and translation in eukaryotes, and several members have...
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