Article
Interaction between smoking and genetic factors in the development of chronic bronchitis.
American journal of respiratory and critical care medicine - 1 Mar 2008
Hallberg Jenny, Dominicus Annica, Eriksson Ulrika K, Gerhardsson de Verdier Maria, Pedersen Nancy L, Dahlbäck Magnus, Nihlén Ulf, Higenbottam Tim, Svartengren Magnus
Abstract excerpt
RATIONALE: Smoking is a primary risk factor for chronic bronchitis, emphysema, and chronic obstructive pulmonary disease, but since not all smokers develop disease, it has been suggested that some individuals may be more susceptible to exogenous factors, such as smoking, and that this susceptibility could be genetically determined. OBJECTIVES: The aim of the present study was to assess, in a population-based...
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