Article
Loop-Mediated Isothermal Amplification Method Targeting the TTS1 Gene Cluster for Detection of <i>Burkholderia pseudomallei</i> and Diagnosis of Melioidosis
27 Nov 2007
Abstract excerpt
Melioidosis is a severe infection caused by Burkholderia pseudomallei. The timely implementation of effective antimicrobial treatment requires rapid diagnosis. Loop-mediated isothermal amplification (LAMP) targeting the TTS1 gene cluster was developed for the detection of B. pseudomallei. LAMP was sensitive and specific for the laboratory detection of this organism. The lower limit of detection was 38 genomic...
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