Article
Evolution of hepatitis C virus infection under host factor influence in an ethnically complex population.
Liver international : official journal of the International Association for the Study of the Liver - 1 Dec 2007
Cursino-Santos Jeny R, Donadi Eduardo A, Martinelli Ana L C, Louzada-Junior Paulo, Martinez-Rossi Nilce M
Abstract excerpt
BACKGROUND: The ethnic influence makes it difficult to reach a consensual definition of host-dependent genetic factors controlling the hepatitis C virus (HCV) disease course. AIMS: To investigate, in an ethnically complex Brazilian population, whether human leucocyte antigen (HLA) molecules are associated with susceptibility to HCV infection, self-limiting viral clearance and predisposition to chronic disease....
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