Article
Association of vitamin D receptor gene Taq I polymorphism with recurrent urolithiasis in children.
International journal of urology : official journal of the Japanese Urological Association - 1 Dec 2007
Seyhan Serkan, Yavascaoglu Ismet, Kilicarslan Hakan, Dogan Hasan S, Kordan Yakup
Abstract excerpt
OBJECTIVE: Urolithiasis has a strong familial component. However, to date, no specific genetic abnormality has been identified. It has been reported that allelic variation in the vitamin D receptor (VDR) gene may affect calcium absorption and excretion. Urolithiasis is a multifactorial disease in which both genetic and environmental factors have an effect on onset and severity of disease. In the present study,...
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