Article
Relationship between methionine synthase, methionine synthase reductase genetic polymorphisms and deep vein thrombosis among South Indians.
Clinical chemistry and laboratory medicine - 1 Jan 2008
Naushad Shaik Mohammad, Jain Jamal Mohamed Nurul, Prasad Chintakindi Krishna, Rama Devi Akella Radha
Abstract excerpt
BACKGROUND: The rationale behind this study was to examine the relationship between polymorphisms in genes that regulate remethylation of homocysteine to methionine, i.e., methionine synthase (MTR A2756G) and methionine synthase reductase (MTRR A66G), and risk of deep vein thrombosis (DVT) in a South Indian cohort (163 DVT cases and 163 controls), as elevated homocysteine has been documented as an independent...
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