Article
Pharmacogenetics of the PPAR genes and cardiovascular disease.
Pharmacogenomics - 1 Nov 2007
Cresci Sharon
Abstract excerpt
The goal of pharmacogenetics is to define the genetic determinants of individual drug responsiveness, and thereby provide personalized treatment to each individual. The peroxisome proliferator-activated receptors (PPARs) are polypeptide products of a set of related genes functioning to regulate several cellular processes that are central to cardiovascular health and disease. Given their pleiotropic roles in lipid...
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