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Distribution of varicella-zoster virus (VZV) wild-type genotypes in northern and southern Europe: evidence for high conservation of circulating genotypes.

Virology - 20 Jan 2009

Loparev Vladimir N, Rubtcova Elena N, Bostik Vanda, Tzaneva Valentina, Sauerbrei Andreas, Robo Alma, Sattler-Dornbacher Eva, Hanovcova Iva, Stepanova Vera, Splino Miroslav, Eremin Vladimir, Koskiniemi Marjaleena, Vankova Olga E, Schmid D Scott

Abstract excerpt

Phylogenetic analysis of 19 complete VZV genomic sequences resolves wild-type strains into 5 genotypes (E1, E2, J, M1, and M2). Complete sequences for M3 and M4 strains are unavailable, but targeted analyses of representative strains suggest they are stable, circulating VZV genotypes. Sequence analysis of VZV isolates identified both shared and specific markers for every genotype and validated a unified VZV...

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PMID: 19019403
DOI: 10.1016/j.virol.2008.10.026

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