Article
Hepatitis B genotypes and surface antigen mutants present in Pakistani blood donors.
PloS one - 1 Jan 2017
Harris Barbara J, Holzmayer Vera, Qureshi Huma, Khan Mohammad Ayyub, Khan Saleem Ahmed, Salamat Nuzhat, Jafri Sarfaraz, Brennan Catherine A
Abstract excerpt
BACKGROUND: The prevalence of chronic Hepatitis B Virus (HBV) infection is 2-4% in the Pakistani population, defining Pakistan as an intermediate prevalence country. In this study, hepatitis B surface antigen (HBsAg) reactive blood donations were screened using a combination of serological and molecular methods to identify immune escape HBV mutant strains and to determine the HBV genotypes and subtypes present in...
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