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Article

Partial correction of the CFTR-dependent ABPA mouse model with recombinant adeno-associated virus gene transfer of truncated CFTR gene.

The journal of gene medicine - 1 Jan 2008

Mueller Christian, Torrez Daniel, Braag Sofia, Martino Ashley, Clarke Tracy, Campbell-Thompson Martha, Flotte Terence R

Abstract excerpt

Recently, we have developed a model of airway inflammation in a CFTR knockout mouse utilizing Aspergillus fumigatus crude protein extract (Af-cpe) to mimic allergic bronchopulmonary aspergillosis (ABPA) 1, an unusual IgE-mediated hypersensitivity syndrome seen in up to 15% of cystic fibrosis (CF)...

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Source

Identifiers

PMID: 18023072
DOI: 10.1002/jgm.1119

Genes

CFTR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18023072-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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