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The type and the position of HNF1A mutation modulate age at diagnosis of diabetes in patients with maturity-onset diabetes of the young (MODY)-3.

Diabetes - 1 Feb 2008

Bellanné-Chantelot Christine, Carette Claire, Riveline Jean-Pierre, Valéro René, Gautier Jean-François, Larger Etienne, Reznik Yves, Ducluzeau Pierre-Henri, Sola Agnès, Hartemann-Heurtier Agnès, Lecomte Pierre, Chaillous Lucy, Laloi-Michelin Marie, Wilhem Jean-Marie, Cuny Pierre, Duron Françoise, Guerci Bruno, Jeandidier Nathalie, Mosnier-Pudar Helen, Assayag Michel, Dubois-Laforgue Danièle, Velho Gilberto, Timsit José

Abstract excerpt

OBJECTIVE: The clinical expression of maturity-onset diabetes of the young (MODY)-3 is highly variable. This may be due to environmental and/or genetic factors, including molecular characteristics of the hepatocyte nuclear factor 1-alpha (HNF1A) gene mutation. RESEARCH DESIGN AND METHODS: We anal...

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Identifiers

PMID: 18003757
DOI: 10.2337/db07-0859

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-18003757-2026-09-04.1. Manifest publication-graph-cohort-2026-09-04.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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