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Article

Co-inherited mutations of Fas and caspase-10 in development of the autoimmune lymphoproliferative syndrome.

BMC immunology - 13 Nov 2007

Cerutti Elisa, Campagnoli Maria F, Ferretti Massimo, Garelli Emanuela, Crescenzio Nicoletta, Rosolen Angelo, Chiocchetti Annalisa, Lenardo Michael J, Ramenghi Ugo, Dianzani Umberto

Abstract excerpt

BACKGROUND: Autoimmune lymphoproliferative syndrome (ALPS) is a rare inherited disorder characterized by defective function of Fas, autoimmune manifestations that predominantly involve blood cells, polyclonal accumulation of lymphocytes in the spleen and lymph nodes with lymphoadenomegaly and/or...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 17999750
DOI: 10.1186/1471-2172-8-28
PMCID: PMC2211507

Genes

NRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-17999750-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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