Article
In silico genetic robustness analysis of microRNA secondary structures: potential evidence of congruent evolution in microRNA.
BMC evolutionary biology - 13 Nov 2007
Shu Wenjie, Bo Xiaochen, Ni Ming, Zheng Zhiqiang, Wang Shengqi
Abstract excerpt
BACKGROUND: Robustness is a fundamental property of biological systems and is defined as the ability to maintain stable functioning in the face of various perturbations. Understanding how robustness has evolved has become one of the most attractive areas of research for evolutionary biologists, as it is still unclear whether genetic robustness evolved as a direct consequence of natural selection, as an intrinsic...
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