Article
No evidence for physical anhedonia as a candidate symptom or an endophenotype in bipolar affective disorder.
Bipolar disorders - 1 Nov 2007
Etain Bruno, Roy Isabelle, Henry Chantal, Rousseva Angela, Schürhoff Franck, Leboyer Marion, Bellivier Frank
Abstract excerpt
OBJECTIVES: Bipolar affective disorder (BPAD) is clinically and genetically heterogeneous and the affected phenotype is poorly defined, hampering studies of its genetic basis. Studies of specific, familial, clinical indicators of BPAD may be useful for identifying heritable forms. Homogeneous forms of the disease may be identified in patients (candidate symptom approach) and some vulnerability markers may be...
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