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Interferon-inducible IFI16 protein in human cancers and autoimmune diseases

1 Nov 2007

Abstract excerpt

Interferon-inducible IFI16 protein (encoded by IFI16 gene located at 1q21 region) is a member of the p200-protein family. The family includes structurally and functionally-related mouse (for example, p202, p203, and p204 proteins) and human (for example, MNDA, AIM2, and IFIX) proteins. Increased expression of p200-family proteins in a variety of cells is known to inhibit cell cycle progression and modulate cell...

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PMID: 17981573
DOI: 10.2741/2705

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