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Article

Expression and characterization of a human BMP-7 variant with improved biochemical properties.

Protein expression and purification - 1 Feb 2008

Swencki-Underwood Bethany, Mills Juliane K, Vennarini Joe, Boakye Ken, Luo Jinquan, Pomerantz Steve, Cunningham Mark R, Farrell Francis X, Naso Michael F, Amegadzie Bernard

Abstract excerpt

Bone morphogenetic protein-7 (BMP-7, OP-1) is a secreted growth factor that is predominantly known for its osteoinductive properties, though it has also been implicated as having a role in mammalian kidney development. Clinical efficacy of recombinant BMP-7 has been demonstrated in the treatment of orthopedic injuries through topical application. However, the pharmaceutical development of recombinant BMP-7 for...

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Identifiers

PMID: 17977014
DOI: 10.1016/j.pep.2007.09.016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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