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Article

Clusterin Isoforms Differentially Affect Growth and Motility of Prostate Cells: Possible Implications in Prostate Tumorigenesis

1 Nov 2007

Abstract excerpt

Besides a fully processed, secreted form of clusterin (sCLU), an alternative proapoptotic form of the protein targeting the nucleus (nCLU) was recently described. The possible differential roles played by the two clusterin forms in growth and motility of nonmalignant and malignant prostate cells are investigated here. sCLU or nCLU was transiently transfected in both androgen-independent prostate cancer cells (PC3...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 17974975
DOI: 10.1158/0008-5472.can-07-0516

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