Article
Clusterin (SGP‐2, ApoJ) expression is downregulated in low‐ and high‐grade human prostate cancer
18 Sept 2003
Abstract excerpt
Clusterin is overexpressed during tissue and cell involution and downregulated in proliferating cells. Its role in cell survival, cell death and neoplastic transformation remains debated. We studied the expression and distribution of clusterin mRNA and protein in human prostate carcinoma (CaP) specimens of different degrees of malignancy. Fresh CaP specimens were obtained from 25 patients subjected to long-term...
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