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Article

[Proximal axonal injuries as experimental models for adult motoneuron degeneration].

Brain and nerve = Shinkei kenkyu no shinpo - 1 Oct 2007

Watabe Kazuhiko

Abstract excerpt

Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disorder characterized by selective loss of motoneurons leading to progressive paralysis and death by respiratory failure. Since the discovery of the mutation of Cu/Zn superoxide dismutase (SOD1) gene in patients with familial ALS, transgenic mice and rats expressing human mutant SOD1 have been the most widely used experimental models to...

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Identifiers

PMID: 17969359

Genes

SOD1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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