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Biological Variation of the Platelet Proteome in the Elderly Population and Its Implication for Biomarker Research

25 Oct 2007

Abstract excerpt

Knowledge about the extent of total variation experienced between samples from different individuals is of great importance for the design of not only proteomics but every clinical study. This variation defines the smallest statistically significant detectable signal difference when comparing two groups of individuals. We isolated platelets from 20 healthy human volunteers aged 56-100 years because this age group...

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PMID: 17962630
DOI: 10.1074/mcp.m700137-mcp200

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