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Article

Kinetic and structural properties of triosephosphate isomerase from Helicobacter pylori.

Proteins - 1 Apr 2008

Chu Chen-Hsi, Lai Yi-Ju, Huang Haimei, Sun Yuh-Ju

Abstract excerpt

Triosephosphate isomerase (TIM) catalyzes the interconversion between dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate in the glycolysis-gluconeogenesis metabolism pathway. The Helicobacter pylori TIM gene (HpTIM) was cloned, and HpTIM was expressed and purified. The enzymatic activity of HpTIM for the substrate GAP was determined (K(m) = 3.46 +/- 0.23 mM and k(cat) = 8.8 x 10(4) min(-1)). The crystal...

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Identifiers

PMID: 17957775
DOI: 10.1002/prot.21709

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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