Article
HIV-1/HSV-2 co-infected adults in early HIV-1 infection have elevated CD4+ T cell counts.
PloS one - 24 Oct 2007
Barbour Jason D, Sauer Mariana M, Sharp Elizabeth R, Garrison Keith E, Long Brian R, Tomiyama Helena, Bassichetto Katia C, Oliveira Solange M, Abbate Maria C, Nixon Douglas F, Kallas Esper G
Abstract excerpt
INTRODUCTION: HIV-1 is often acquired in the presence of pre-existing co-infections, such as Herpes Simplex Virus 2 (HSV-2). We examined the impact of HSV-2 status at the time of HIV-1 acquisition for its impact on subsequent clinical course, and total CD4+ T cell phenotypes. METHODS: We assessed the relationship of HSV-1/HSV-2 co-infection status on CD4+ T cell counts and HIV-1 RNA levels over time prior in a...
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