A Probiotic <i>Lactobacillus</i> Strain Can Acquire Vancomycin Resistance during Digestive Transit in Mice

Abstract excerpt

The present study demonstrates for the first time the transfer of vancomycin resistance (vanA cluster) from enterococci to a Lactobacillusacidophilus commercial strain. Transfers were observed in vitro, but also in vivo in the gut of mice (in the absence of antibiotic pressure) where transconjugants arose at relatively high frequencies and could persist in the digestive environment. Since transfer of vancomycin...

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